Beverages and osteoporosis: ginger for bone density and osteoclasts

INTI — Organic Ginger, Turmeric & Lemon Shot

INTI — Organic Ginger, Turmeric & Lemon Shot

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Ginger and osteoporosis

Osteoporosis affects 200 million people, especially post-menopausal women. Loss of bone density → fractures of the hip, vertebrae, wrist. Curcumin acts on bone remodeling by slowing resorption.

Osteoprotective mechanisms

  • RANKL/OPG — curcumin inhibits RANKL (signal that activates osteoclasts = cells that destroy bone)
  • Bone NF-κB — inhibits the cascade that stimulates osteoclast differentiation
  • Osteoblasts — stimulates the activity of osteoblasts (cells that build bone)
  • Systemic inflammation — chronic inflammation accelerates bone loss
  • Post-menopause — partially compensates for the effect of the drop in estrogen on the bone
  • Calcium absorption — ginger improves intestinal absorption of minerals

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