Direct answer: ginger shot without sugar affects the microbiome and the gut-brain axis through four pathways: (1) slight prebiotic effect — promotes growth of Lactobacillus and Bifidobacterium, (2) reduction of gut permeability (leaky gut) via strengthening of tight junctions, (3) modulation of intestinal serotonin production (95% of all serotonin is produced in the gut), (4) regulation of the vagus nerve via intestinal 5-HT3 receptors. Result: improved cognition, mood and digestive health.
The gut-brain axis: the gut as a second brain
Gut and brain communicate via:
- Vagus nerve: 80% of signals go from the gut to the brain
- Intestinal serotonin: 95% of all serotonin is produced by enterochromaffin cells → direct influence on mood
- Microbiome-SCFA: gut bacteria produce short-chain fatty acids (butyrate) that influence brain function
Effects of ginger on the microbiome and gut-brain axis
1. Prebiotic effect
- ↑ Lactobacillus and Bifidobacterium
- ↓ Pro-inflammatory bacteria
2. Reduction of gut permeability (leaky gut)
Ginger strengthens tight junction proteins (ZO-1, occludin) and reduces zonulin: -25% gut permeability.
3. Modulation of intestinal serotonin
- Increases 5-HT intestinal secretion → improved digestive motility
- Inhibits 5-HT3 receptors → less nausea, less visceral hypersensitivity (IBS)
INTI gut-brain axis protocol
- 1 INTI shot 's ochtends nuchter (maximum contact with intestinal mucosa)
- Microbiome synergy: ginger + multi-strain probiotics (10 billion CFU) + prebiotics (inulin fibers) = optimized gut-brain axis trio
FAQ microbiome & ginger
Is ginger a prebiotic?
A partial prebiotic. Ginger contains polysaccharides that selectively feed certain beneficial bacteria (Lactobacillus, Bifidobacterium), but its prebiotic action is less specific than inulin or FOS.
Can ginger cause dysbiosis (microbiome imbalance)?
Not at nutritional doses. Ginger has a selective antibacterial effect (mainly on pathogens) and promotes beneficial bacteria. At very high doses (> 10 g/day), a broader effect is theoretically possible — not documented at shot doses.
INTI — For a Gut and Brain in Harmony
Natural prebiotic. Tight junctions. Intestinal serotonin. Belgian cold press.
Related articles
Further reading on related topics :
- Ginger and Gut Microbiome : Prebiotic, Dysbiosis and Gut-Brain Axis
- Ginger and gut microbiome : prebiotic effects on gut flora
- INTI and the Gut-Brain Axis: How Sugary Drinks ginger anxiety and Depression Worsen in Belgium
- sibo-bacteriele-overgroei-dunne-darm-suiker-gember-prokinetisch-darmgezondheid-belgie-2025">INTI and ginger SIBO (small intestinal bacterial overgrowth): how sugar feeds bacteria and ginger restores gut health
- Ginger and ginger digestion: proven effects on intestines and microbiome — and why ginger-2025">comparatif INTI vs GIMBER-sugar sabotages this
- INTI and gut microbiome: why sugary drinks destroy your flora — ginger as a restorer
- Ginger and gut microbiome: Akkermansia, Faecalibacterium, butyrate and gut-brain axis — INTI
- Ginger and menopause: hot flashes, bone density, mood and cognition (TRPV1, RANKL, BDNF, MAO-A)