Ginger and kidney function: kidney protection and prevention of renal failure

The chronic kidney disease affect 10% of the world's population. The ginger has properties nephroprotective remarkable, validated by an increasing number of preclinical and clinical studies.

Kidney protection of ginger

The kidneys are vulnerable to cortisol-natural">ginger oxidative stress, withanti-inflammatory-inflammation-natural-remedy">inflammation and fibrosis. Ginger acts on all three:

• Renal antioxidant : increases glutathione and SOD in kidney tissue by 40% (Renal Failure, 2021)
• anti-inflammatory-science-use">anti-inflammatory ginger : reduces TNF-α and IL-1β in renal glomeruli
• Anti-fibrotic : inhibits TGF-β1, the main mediator of renal fibrosis
• Renal vasodilation : improves renal blood flow via nitric oxide

Drug nephrotoxicity

NSAIDs (ibuprofen, diclofenac), certain antibiotics and chemotherapy damage the kidneys. Ginger protects against this nephrotoxicity: a study (Food and Chemical Toxicology, 2020) shows a 50% reduction in cisplatin nephrotoxicity with the co-administration of ginger.

This is a considerable advantage: ginger can replace NSAIDs for pain, eliminating kidney risk while providing a comparable pain-relieving effect.

ginger diabetes and kidneys

Diabetic nephropathy is the leading cause of kidney failure. Ginger:

• Reduces the blood sugar (protects the glomeruli from hyperglycemia)
• Inhibits AGEs (advanced glycation end products) which destroy kidney capillaries
• Reduces proteinuria (leakage of proteins into urine — marker of kidney damage)

NRTIs and kidney health

• Zero sugar added : sugar aggravates diabetic nephropathy
• turmeric-black-pepper-synergy-benefits">Turmeric : curcumin is nephroprotective (reduces proteinuria by 20%)
• Hydration : INTI diluted in 200 ml of water contributes to renal hydration

Dosage : 1-2 NRTI shots/day. In case of advanced kidney failure (GFR < 30), consult your nephrologist — ginger in dietary doses is generally safe.

Conclusion

Ginger is a natural nephroprotectant that fights stress oxidative, inflammation and renal fibrosis. INTI Drink offers this daily protection sugar free nor nephrotoxic.