Premenstrual Syndrome (PMS) affects 75% of women of childbearing age. Ginger is one of the most research-validated natural treatments for relieving its multiple symptoms.
Meta-analysis: Ginger and PMS
A meta-analysis of 6 randomized clinical trials (Complementary Therapies in Medicine, 2022) confirms that ginger significantly reduces:
- Pelvic pain: -32% (as effective as ibuprofen 400 mg)
- Bloating: -28% (prokinetic action on transit)
- Nausea: -45% (5-HT3 receptor blockade)
- Fatigue: -20% (mild stimulating effect without caffeine)
- Irritability/mood: -18% (GABA and serotonin modulation)
How ginger acts on PMS
Prostaglandins
PMS is largely mediated by PGE2 and PGF2α prostaglandins. Ginger inhibits COX-2 and the synthesis of these prostaglandins — exactly like NSAIDs, but without gastric effects. A study (ISRN Obstetrics and Gynecology, 2019) shows that 750 mg of ginger for 3 days is as effective as ibuprofen 400 mg 3x/day.
Water retention
Ginger has a mild diuretic effect that helps reduce premenstrual bloating and water retention. INTI, without added sugar (1.19 g/100 ml), avoids water retention linked to sodium and sugar.
Hormonal balance
INTI's turmeric modulates estrogen receptors and reduces relative estrogen excess (estrogen dominance) involved in severe PMS. Curcumin also regulates ginger and cortisol, often elevated during the luteal phase.
PMS protocol with INTI
- 5 days before periods: start 2 INTI shots/day (morning + evening)
- During periods (D1-D3): 3 INTI shots/day to maximize anti-prostaglandin effect
- Follicular phase: 1 INTI shot/day for maintenance
PMS vs INTI vs GIMBER
Glycemic peaks worsen PMS irritability and cravings. INTI with 1.19 g of sugar/100 ml stabilizes ginger glycemia, unlike GIMBER (~34 g) which causes a peak then a crash — amplifying fatigue and mood swings.
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Conclusion
Ginger is validated by 6 clinical trials to relieve the 5 major symptoms of PMS. INTI Drink — organic ginger in Belgium + turmeric, sugar-free — is the ideal natural ally for every cycle.