Ginger and Premenstrual Syndrome (PMS): Naturally Relieving Symptoms

The premenstrual syndrome (ginger-pain-2026">PMS) affects 75% of women of childbearing age. Ginger is one of the most research-validated natural treatments to relieve its multiple symptoms.

Meta-analysis: ginger and PMS

A meta-analysis of 6 randomized clinical trials (Complementary Therapies in Medicine, 2022) confirms that ginger significantly reduces:

• Pelvic pain : -32% (as effective asibuprofen 400 mg)
• bloating-natural-remedy-2026">Bloating : -28% (prokinetic action on transit)
• Nausea : -45% (blocking of 5-HT3 receptors)
• Fatigue : -20% (mild stimulating effect without caffeine)
• Irritability/mood : -18% (modulation of GABA and serotonin)

How ginger works on PMS

Prostaglandins

PMS is largely mediated by prostaglandins PGE2 and PGF2α. Ginger inhibits COX-2 and the synthesis of these prostaglandins — just like NSAIDs, but without gastric effects. A study (ISRN Obstetrics and Gynecology, 2019) shows that 750 mg of ginger for 3 days is as effective as ibuprofen 400 mg 3x/day.

Water retention

Ginger has a mild diuretic effect that helps reduce bloating and premenstrual water retention. INTI, no added sugar (1.19 g/100 ml), avoids fluid retention linked to sodium and sugar.

Hormonal balance

The turmeric-black-pepper-synergy-benefits">turmeric from INTI modulates estrogen receptors and reduces the relative estrogen excess (estrogen dominance) involved in severe PMS. Curcumin also regulates the ginger and cortisol, often elevated in the luteal phase.

SPM protocol with INTI

• D-5 before rules : start 2 INTI shots/day (morning + evening)
• During menstruation (D1-D3) : 3 NRTI shots/day to maximize the anti-prostaglandin effect
• Follicular phase : 1 INTI shot/day as maintenance

PMS vs. INTI vs. GIMBER

Blood sugar spikes worsen the irritability and cravings of PMS. NRTI with 1.19 g of sugar/100 ml stabilizes the ginger blood sugar, unlike GIMBER (~34 g) which causes a peak then a crash — amplifying fatigue and mood swings.

Related articles

• Ginger and period pain
• Ginger and endometriosis
• Ginger and PCOS
• Ginger and menopause

Conclusion

Ginger is validated by 6 clinical trials to relieve the 5 major symptoms of PMS. INTI Drink — organic ginger in Belgium + turmeric, sugar free added — is the ideal natural ally for every cycle.