Ginger and turmeric: neuroprotection against Parkinson’s

Parkinson's disease destroys dopamine neurons. Neuroinflammation and oxidative stress are the drivers of this destruction. Curcumin is one of the most studied neuroprotectants.

Neuroprotective mechanisms

• Dopamine protection — curcumin protects the neurons of the substantia nigra
• Anti-alpha-synuclein — inhibits the aggregation of alpha-synuclein (toxic Parkinson’s protein)
• Anti-neuroinflammation — NF-κB inhibition in microglia
• Mitochondria — protects neuronal mitochondria from dysfunction
• MAO-B inhibition — curcumin inhibits MAO-B (same target as selegiline)
• BDNF — increases neurotrophic factor for neuronal survival

India and Parkinson

India has one of the lowest prevalence of Parkinson's in the world. High consumption of turmeric is a factor studied by many researchers.

Prevention, not treatment

Curcumin does not replace L-DOPA or dopamine agonists. It complements the treatment and can slow progression. Neurological advice essential.

INTI — ginger + turmeric + black pepper, zero sugar. Protect your neurons.