INTI for biohackers: the optimized synergistic formula

Do you measure, optimize, and seek the molecular edge? INTI was designed based on recent scientific literature. Here's why it's one of the most optimized stacks on the Belgian — and probably European — market.

The 6 ingredients, chosen for their synergy

Ingredient	Primary Target Pathway	Rationale
[6]-gingerol	NF-kB, COX-2, AMPK	3000+ studies
Curcumin	NF-kB, IKK, Nrf2	The most studied natural anti-inflammatory
Piperine	UDP-glucuronosyltransferase	×20 curcumin bioavailability (Shoba 1998)
Capsaicin	TRPV1, thermogenesis	Vasodilation, metabolism
Lemon (Vitamin C)	Antioxidant	Collagen biosynthesis co-factor
Organic Erythritol	0 GI, 0 NF-kB	Taste without glycemic load

Simultaneously activated pathways

• NF-kB ↓: multi-target (gingerol, curcumin)
• AMPK ↑: partial metformin mimetic
• Nrf2 ↑: endogenous antioxidants (glutathione, SOD)
• COX-2 ↓: pain relief without gastric toxicity
• TRPV1 modulation: vasodilation, thermogenesis
• JAK/STAT3 ↓: Th17 inhibition, anti-autoimmune

Optimized pharmacokinetic profile

The challenge for biohackers with capsule curcumin: oral bioavailability ~1% without co-factor. Common solutions: Meriva, BCM-95, etc. (lipid-based, expensive).

INTI solves this problem natively: curcumin + organic piperine in a liquid formulation. Superior absorption compared to a separate encapsulated mixture.

Markers to monitor (for data nerds)

• hsCRP (high-sensitivity CRP): target <1 mg/L
• HbA1c: target <5.4%
• Fasting Glucose: 70-90 mg/dL
• HOMA-IR: target <1.5
• Triglycerides/HDL ratio: <1.5
• Vitamin D: 40-60 ng/mL
• Omega-3 index: >8%

Measuring these markers before + 3 months after daily INTI allows you to objectify the effect on your personal profile.

Interesting complementary stack

• + Magnesium bisglycinate (400 mg/day) — common deficiency
• + Omega-3 EPA/DHA (2g/day) — complementary anti-inflammation
• + Vitamin D3 (according to serum levels) — NF-kB and immunity modulation
• + Multi-strain probiotics — anti-inflammatory microbiome
• + 7-9h sleep and 16:8 intermittent fasting — major metabolic levers

Biohacker Protocol

1. Baseline: full blood test, markers listed above
2. Phase 1 (weeks 1-4): 15ml INTI morning on an empty stomach
3. Phase 2 (weeks 5-12): 15ml morning + 10ml post-workout
4. Re-test at week 12: objectify the effect
5. Maintenance: adjust according to results

Biohacker FAQ

INTI vs Meriva curcumin in capsule?

Meriva is ~30× more bioavailable than standard curcumin via phospholipid complexation. INTI is ~20× more bioavailable via piperine. Comparable magnitudes. INTI also adds gingerol + capsaicin + vitamin C.

Cycle or continuous?

Continuous. No documented tolerance. No need to cycle.

Compatible with intermittent fasting?

During strict fasting window (water only): no, breaks the fast (1.19g sugar = ~5 kcal per 20ml = does not break autophagic fasting). During eating window: yes, ideally.

Compatible with ketosis?

Perfectly (1.19g sugar/100ml + erythritol GI=0).