Ginger: review of scientific research in 2026

The ginger (Zingiber officinale) is one of the most studied plants in the world. More than 3,000 studies are referenced on PubMed. Here's what science knows for sure, what's promising, and what remains to be proven.

What is firmly established (multiple meta-analyses)

• Nausea and vomiting : antiemetic effect validated — ginger and ginger and pregnancy, chemo, post-operative, ginger motion sickness. Level of evidence: A
• anti-inflammatory-inflammation-natural-remedy">Systemic inflammation : reduction of CRP, IL-6, TNF-α. Mechanism NF-κB confirmed in vivo and in vitro. Level of evidence: A
• ginger blood sugar and insulin : reduction of fasting blood sugar, HbA1c, ginger HOMA-IR. More than 10 randomized trials. Level of evidence: A-
• Joint pain : efficiency comparable toibuprofen in theosteoarthritis of the knee (Altman 2001, Wigler 2003). Level of proof: B+
• Dyslipidemia : reduction LDL, triglycerides in several meta-analyses. Level of proof: B+

What is promising (preliminary clinical studies)

• Cancer : pro-apoptotic effects in vitro on colorectal, breast and ovarian cancer cells — no conclusive clinical trial to date
• ginger and Alzheimer's / neurodegeneration : reduction of amyloid aggregates in vivo in mice, some positive human pilot tests
• Fertility masculine : improvement in sperm motility in 3 trials (Iran, Egypt) — consistent results but little replication
• liver-fat">ginger NASH / liver fat : reduction in hepatic markers in 2 randomized trials
• Depression : effects on serotonin/dopamine in vivo — a positive clinical trial (Jahangir 2015)

What remains to be proven

• Dosage optimal: studies use 500mg to 3g/day — no consensus
• Optimal duration of supplementation
• Drug interactions: insufficient data for high-dose anticoagulants
• Long-term effects (>12 months): few studies

Key assets identified

• [6]-gingerol : main asset anti-inflammatory ginger and antiemetic
• [6]-shogaol : formed during drying/cooking, more powerful than gingerol on certain targets
• Zingerone : antioxidant active, formed by heat
• Paradol : thermogenic active

INTI and science

INTI is formulated to maximize validated effects: fresh ginger (preserved gingerol) + turmeric-black-pepper-synergy-benefits">turmeric + piperine (bioavailability ×20) + 0 added sugar (so as not to counteract the glycemic effects).

→ Complete Guide to Ginger
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