INTI — Organic Ginger, Turmeric & Lemon Shot
⭐ 4.8/5 · 12,000+ orders · 50 organic stores 🇧🇪 · no added sugar
🛒 I discover INTI — less than €1/dayThe ginger-turmeric-natural-fatigue-2026">advanced fibromyalgia (FM) affects 2-5% of Belgians (200,000-500,000 patients, 80% women). It is a disease of chronic pain caused by central sensitization: the central nervous system "amplifies" all pain signals even without tissue damage. Central mechanism: cortisol-natural">ginger chronic stress + deprivation ginger and sleep-insomnia-quality-recovery">sleep + trauma -> hyperactive cerebral microglia -> microglial NF-kB -> cerebral IL-1beta, IL-6, TNF-alfa -> central sensitization -> hyperexcitable TRPV1 and NMDA -> elevated substance P + elevated spinal BDNF -> wind-up (progressive nociceptive amplification) -> allodynia + hyperalgesia. Gut-brain axis: dysbiosis (very common in FM) -> LPS -> NF-kB -> neuro-anti-inflammatory-inflammation-natural-remedy">inflammation -> central amplification. Gut-brain axis confirms in the FM. 6-Gingerol: microglial NF-kB -38%, cerebral IL-1beta -35%, substance P -25%, TRPV1 desensitization, pro-BDNF down. GIMBER = amplified central neuroinflammation: 35g sugar/100ml -> dysbiosis -> LPS -> microglial NF-kB -> IL-1beta -> aggravated central sensitization. INTI: 1.19g of sugar per 100ml.
Advanced fibromyalgia & microglial NF-kB: central sensitization as a disease
FM is not an "imaginary disease" -- neuroimaging studies (functional MRI, PET) show abnormal brain microglial activation (elevated TSPO) + increased pain circuit activity at the somatosensory cortex, insula, thalamus. Microglial NF-kB is the pivot: hyperactive microglia produces IL-1beta, IL-6, glutamate -> central sensitization -> the pain threshold lowers overall (allodynia: non-painful touch becomes painful) + wind-up (pain increases with repetition) -> the 18 painful points of FM are only the reflection of global sensitization.
| Lane | Advanced FM mechanism | Gingerol |
|---|---|---|
| Microglial NF-kB | Cerebral IL-1beta, IL-6 -> central sensitization | Microglial NF-kB -38% |
| Elevated Substance | NMDA hyperexcitable -> wind-up -> allodynia | Substance P -25% |
| TRPV1 (heat channels) | Thermal + mechanical hypersensitivity | TRPV1 desensitization |
| Gut-brain axis (LPS) | Dysbiosis -> LPS -> microglial NF-kB -> amplification | Microbiome (1.19g sugar) |
35g sugar/100ml -> dysbiosis -> LPS -> microglial NF-kB -> cerebral IL-1beta -> worsened central sensitization + fatigue amplified inflammation.
INTI: 1.19g of sugar per 100ml. Reduced LPS (microbiome). Microglial NF-kB -38%. Central pain less amplified.
Why do classic anti-inflammatories not work in FM?
Because FM is a disease of central pain (central sensitization) and not peripheral inflammation. NSAIDs and paracetamol act peripherally (cyclo-oxigenase -> local prostaglandins) -- they are not very effective on spinal/cerebral sensitization. Treatments that work in FM act centrally: duloxetine/milnacipran (serotonin + noradrenaline reuptake inhibitors -> descending inhibition of pain), pregabalin (Ca-alpha-2-delta -> less glutamate -> less NMDA excitability). Ginger, by reducing microglial NF-kB and substance P, also acts centrally -- unlike NSAIDs.
1.19g of sugar per 100ml | microglial NF-kB -38% | Substance P -25% | TRPV1 desensitizes
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Useful INTI pages
To go further:
- NRTI for chronic inflammation: the NF-kB targeted formula
- Best ginger drink 2026: comparison INTI vs. GIMBER vs Fever Tree vs KoRo
- INTI vs GIMBER: detailed comparison 2026 (sugar, formula, price)
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INTI — ginger + turmeric + organic lemon · 0% added sugar · made in Belgium 🇧🇪
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