Neuromyelitis Optica (Devic's Disease): Anti-AQP4 Antibodies and Complementary Approach

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Optical Neuromyelitis (Devic): Anti-AQP4 Antibodies and Complementary Approach

The neuromyelitis optica (NMOSD, Devic syndrome) is distinct from MS. Preferential damage to the optic nerve and spinal cord. Treatment: eculizumab, satralizumab, inebilizumab, rituximab.

Mechanisms

  • Anti-AQP4 autoantibodies (rarely anti-MOG)
  • Activation of the add-in
  • Astrocytes attacked
  • Dominant Th17 and IL-6

Action ginger + turmeric + turmeric-synergy-x20-inti-unique">piperine

  • Curcumin ↓ Th17 and NF-kB
  • Piperine for bioavailability
  • [6]-gingerol IL-6 partial inhibition

INTI

INTI composition : ginger, turmeric, lemon, black pepper, cayenne, erythritol — organic. ginger-1-19g-sugar-100ml-exact-number">1.19g sugar/100ml. Piperine + curcumin synergy ×20 bioavailability (Shoba 1998).

FAQs

Can INTI prevent NMOSD flare-ups?

Possible adjuvant. Monoclonal antibodies remain essential.

Informative article.

Useful pages INTI

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