Ginger and cholesterol : LDL, triglycerides and health cardiovascular

Dyslipidemia (cholesterol imbalance) is a major risk factor for cardiovascular disease. The ginger is one of the rare natural active ingredients with meta-analyses confirming its lipid-lowering effect.

Clinical Evidence on Cholesterol

Meta-analysis Arzati (2017) — 12 randomized trials:

• LDL cholesterol: reduction of -10 to -17%
• Triglycerides: reduction of -8 to -15%
• VLDL: significant reduction
• HDL (good cholesterol): slight beneficial increase

Meta-analysis Atashak (2011) out of 6 trials: significant reduction in serum lipids in patients with dyslipidemia and ginger obesity.

Lipid-lowering mechanisms

• HMG-CoA reductase inhibition : key enzyme in cholesterol synthesis (same target as statins, but weaker effect)
• Increased hepatic LDL receptors : the liver-detox-hepatic-steatosis-protection-2026">liver captures more circulating LDL
• Reduced intestinal absorption : slightly inhibits the absorption of dietary cholesterol
• Activation of lose weight-studies">ginger and bile metabolism : increased excretion of cholesterol via bile

Ginger vs Statins

Ginger does not replace statins for severe dyslipidemia. On the other hand, it can be a useful complement for:

• People with mild to moderate dyslipidemia who do not want statins
• Slightly potentiate the effect of statins (consult the doctor)
• Improving the lipid profile in the context of a diet keto or low-carb

INTI and lipid profile

The ginger + combination turmeric-black-pepper-synergy-benefits">turmeric (NRTI) is particularly powerful on cholesterol: curcumin (with piperine) has hypolipidemic effects additive to gingerol. The 0g of added sugar also eliminates the contribution of fructose to the elevation of triglycerides — a factor often overlooked.

→ Ginger and metabolic syndrome
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