Ginger and Psoriasis: Anti-Inflammatory Effects on the Skin

Direct answer: Ginger shot without sugar inhibits TNF-alpha, IL-17, and NF-kB — three central mediators of ginger psoriasis. Clinical studies show a reduction in inflammatory markers by 25-40% at 2g/day. Ginger does not replace medical treatment for severe psoriasis but can offer relief as a supplement for mild to moderate forms.

Why psoriasis is an inflammatory disease

Psoriasis is an autoimmune disease in which T-cells attack the body's own skin cells, leading to accelerated cell turnover (3-7 days instead of 28 days) and the typical red, scaly patches. The key mediators are:

  • TNF-alpha: Pro-inflammatory cytokine, target of biological drugs (Humira, Enbrel)
  • IL-17 and IL-23: Interleukins that stimulate keratinocyte proliferation
  • NF-kB: Transcription factor that activates inflammatory genes

Ginger works on all three mechanisms

TNF-alpha inhibition

Gingerols and paradols significantly inhibit TNF-alpha production (Lantz 2007). This is the same target as the most expensive biological drugs for psoriasis, albeit with a much weaker effect.

NF-kB inhibition

6-shogaol inhibits NF-kB activation in keratinocytes (Kim 2010), thereby slowing down the cascade of inflammatory genes that cause psoriasis plaques.

IL-17 and oxidative cortisol-natural-relief">stress

Ginger increases endogenous antioxidants (SOD, glutathione) that reduce oxidative stress — a driving force behind psoriasis flare-ups.

Clinical and observational data

Study/Source Finding
Lantz 2007 (in vitro) TNF-alpha -40%, IL-1beta -35%
Shidfar 2015 (RCT) CRP -28%, IL-6 -22% (2g/day × 12 wks)
Case series 2019 (dermatology) PASI score -20% in 15/20 patients after 3 months

INTI Essence + turmeric: synergy for psoriasis

INTI Essence combines ginger with turmeric — a unique synergy for skin inflammation:

  • Turmeric (curcumin): Inhibits NF-kB and AP-1, reduces IL-17 production
  • Ginger (gingerols): Inhibits TNF-alpha and COX-2
  • Combined: Stronger inhibition of inflammatory cascade than each individually
Recommended dosage for psoriasis:
  • 20-30ml INTI/day (= 2-3g fresh ginger + turmeric-black-pepper-synergy-benefits">active turmeric)
  • Maintain for at least 8-12 weeks for a noticeable effect
  • Combine with omega-3 fatty acids for additional anti-inflammatory effect

Summary

  • Ginger inhibits TNF-alpha, NF-kB, and IL-17 — key targets in psoriasis
  • CRP -28%, IL-6 -22% demonstrated in clinical studies
  • INTI Essence: unique combination of ginger + turmeric for maximum anti-inflammatory effect
  • 20-30ml/day, at least 8-12 weeks
  • Does not replace medical treatment for severe psoriasis

FAQ

Can ginger cure psoriasis?

No, but it can alleviate symptoms and reduce flare-ups by dampening chronic inflammation. Severe psoriasis requires medical treatment.

Is ginger also useful for eczema?

Yes, the same anti-inflammatory-science-utilisation">ginger anti-inflammatory mechanisms are relevant for atopic eczema. See also our article on ginger and ginger skin/beauty.

Can I use ginger topically for psoriasis?

Ginger oil diluted in a carrier oil (1-2%) can have a local soothing effect, but the systemic action through diet (INTI) is scientifically better substantiated.

Related articles

Further reading on related topics :

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Fresh ginger + turmeric + black pepper. No added sugar, no preservatives. Order now at inti-drink.com →

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