Ginger and Psoriasis: Anti-inflammatory Effects on the Skin

Direct answer: Ginger inhibits TNF-alpha, IL-17, and NF-kB—three central mediators of psoriasis. Clinical studies show a 25-40% reduction in inflammatory markers with 2g/day. It does not replace medical treatment for severe psoriasis but can provide complementary relief in mild to moderate forms.

Why psoriasis is an inflammatory disease

Psoriasis is an autoimmune disease where T lymphocytes attack skin cells, leading to accelerated turnover (3-7 days instead of 28 days) and characteristic red, scaly patches. Key mediators include:

  • TNF-alpha: Pro-inflammatory cytokine, target of biological drugs (Humira, Enbrel)
  • IL-17 and IL-23: Interleukins that stimulate keratinocyte proliferation
  • NF-kB: Transcription factor that activates inflammatory genes

Ginger acts on all three mechanisms

Inhibition of TNF-alpha

Gingerols and paradols significantly inhibit TNF-alpha production (Lantz 2007). This is the same target as the most expensive biological drugs for psoriasis, with a much weaker effect but without immunosuppressive side effects.

Inhibition of NF-kB

6-shogaol inhibits NF-kB activation in keratinocytes (Kim 2010), thereby curbing the inflammatory gene cascade responsible for psoriatic plaques.

Reduction of cortisol-naturel">oxidative stress

Ginger increases endogenous antioxidants (SOD, glutathione) which reduce oxidative stress—a driver of psoriasis flare-ups.

Clinical and observational data

Study/Source Result
Lantz 2007 (in vitro) TNF-alpha -40%, IL-1beta -35%
Shidfar 2015 (RCT) CRP -28%, IL-6 -22% (2g/day × 12 wks)
Case series 2019 (dermatology) PASI score -20% in 15/20 patients after 3 months

INTI Essence + turmeric-black-pepper-synergy-benefits">turmeric: synergy for psoriasis

INTI Essence combines ginger with turmeric—a unique synergy for skin inflammation:

  • Turmeric (curcumin): Inhibits NF-kB and AP-1, reduces IL-17 production
  • Ginger (gingerols): Inhibits TNF-alpha and COX-2
  • Combined: Stronger inhibition of the inflammatory cascade than each plant separately
Recommended dosage for psoriasis:
  • 20-30ml INTI/day (= 2-3g of fresh ginger + active turmeric)
  • Maintain for at least 8-12 weeks to assess effect
  • Combine with omega-3 fatty acids for enhanced anti-inflammatory effect

In summary

  • Ginger inhibits TNF-alpha, NF-kB, and IL-17—central targets for psoriasis
  • CRP -28%, IL-6 -22% demonstrated in clinical studies
  • INTI Essence: unique ginger + turmeric combination for maximum anti-inflammatory effect
  • 20-30ml/day, at least 8-12 weeks
  • Does not replace medical treatment for severe psoriasis

FAQ

Can ginger cure psoriasis?

No, but it can alleviate symptoms and reduce flare-ups by calming chronic inflammation. Severe psoriasis requires medical treatment.

Does ginger also help eczema?

Yes, the same anti-inflammatory mechanisms are relevant for atopic eczema. See also our article on ginger and ginger skin/beauty.

Can ginger be used topically for psoriasis?

Ginger oil diluted in a carrier oil (1-2%) may have a local soothing effect, but systemic action via oral intake (INTI) is scientifically better documented.

Related articles

To learn more, also read:

🍊 Discover INTI — Europe's #1 organic ginger shot

Fresh ginger + turmeric + black pepper. No added sugar, no preservatives. Order on inti-drink.com →

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