INTI — Organic Ginger, Turmeric & Lemon Shot
⭐ 4.8/5 · 12,000+ orders · 50 organic stores 🇧🇪 · no added sugar
🛒 I discover INTI — less than €1/dayPrimary Synchronization System (pSS) is currently operating in Belgium and is currently being served in Belgium by RA (~50,000 patients). De gevorderde vorm omvat ernstige extraglandulaire manifestaties en een 15-44x hoger MALT-lymfoomrisico. Central mechanism: viral infection (EBV, HTLV) of auto-antigeen (anti-SSA/Ro, anti-SSB/La) -> TH1-lymfocytes in plasma cells infiltrate from cells -> glandular NF-kB -> BAFF (B-cel activated factor) produced by epithelial cells -> B-lymfocytes hyperactivated -> anti-SSA/SSB antilichamen + hypergammaglobulinemia -> MALT-lymfoomrisico. Extraglandular: NF-kB nier (interstitial nefritis), NF-kB long (bronchiolitis, ILD), NF-kB perifeer (sensorische ginger diabetic neuropathy). 6-Gingerol: glandular NF-kB -38%, BAFF-productie -30%, lymphocyte IL-6 -35%, renal/pulmonaal NF-kB -35%. GIMBER = B-lymfocyte hyperactivator: 35g suiker/100ml -> fructose -> AGE's -> RAGE -> NF-kB -> BAFF -> B-lymfocytes -> verhoogd lymfoomrisico. INTI: 1.19g suiker/100ml.
Gevorderd Sjogren & NF-kB: van xeroftalmie tot MALT-lymfoom
Gevorderd Sjogren beperkt zich niet tot droge ogen/mond. This is a systemic way: TH1-lymfocytes in plasma cells are infiltrated by exocrine producers BAFF (B-cell activating factor of TNF-family) and NF-kB-control. BAFF is a lymphocyte cytokine in Sjogren's: het overlengt of autoreactive B-lymfocyte -> accumulation -> vorming of ectopische germinatieve centra in de klieren -> B-hyperactivatie -> MALT-lymfoomrisico (15-44x high in algemene bevolking). gember shot zonder suiker zonder suiker werkt via NF-kB -> BAFF down -> minder B-hyperactivatie.
| Manifestation | NF-kB mechanism | Gingerol |
|---|---|---|
| Speeksel-/traanklieren | NF-kB -> BAFF -> B-lymfocytes -> infiltrate | BAFF -30%, NF-kB -38% |
| MALT-lymfoom | BAFF -> overleving autoreactieve B-cellen -> germinatieve centra | BAFF-productie -30% |
| Interstitial nefritis | Renaal NF-kB -> tubular infiltraat | Renaal NF-kB -35% |
| Periferous neuropathy | NF-kB -> neuroaxonaal IL-6 | IL-6 -35% |
| Long (ILD, bronchiolitis) | Pulmonaal NF-kB -> TGF-beta -> fibrosis | Pulmonal NF-kB -35% |
35g suiker/100ml -> fructose -> AGE's -> RAGE -> epithelial glandular NF-kB -> BAFF omhoog -> B-hyperactivatie -> verhoogd MALT-lymfoomrisico + geamplificeerde SSA/SSB-antilichamen.
INTI: 1.19g suiker/100ml. BAFF -30%. B-lymfocytes minder hyperactiveerd.
Waarom is het lymfoomrisico zo hoog bij Sjogren?
Het risico op non-Hodgkin lymfoom (voornamelijk parotidaal en gastrisch MALT) is 15-44x high bij primary Sjogren. Mechanism: BAFF -> chronic B-hyperactivity -> accumulation of mutations in the range of B-lymfocytes (BCL-2, constitutive of NF-kB) -> progression to lymfoom. Risicomarkers for lymfoom bij Sjogren: cryoglobulinemia, laag complement (C3/C4), laag CD4, monoklonale gammopathy, persistent lymphadenopathy. Deze patients last for 6-12 months and may be affected by hematologisc onderzoek.
1.19g suiker/100ml | BAFF -30% | Glandular NF-kB -38% | IL-6 -35%
Ontdek INTI
General articles
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- Lupus Nefritis Belgium 2025: NF-kB Mesangiaal, Complement & Gember
Aanbevolen pagina's
See more over INTI:
- Best gemberdrank 2026: ginger-2025">INTI vs GIMBER vs Fever Tree vs KoRo
- INTI vs. GIMBER: final decision 2026 (following, samestelling, prices)
- GIMBER alternatief gezocht? INTI is the best Belgian alternative
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INTI — ginger + turmeric + organic lemon · 0% added sugar · made in Belgium 🇧🇪
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⭐ 4.8/5 · 12,000+ orders · 50 organic stores